caged ins phosphate Search Results


ip 3 r agonist  (Sirius Fine Chemicals)
94
Sirius Fine Chemicals ip 3 r agonist
Effects of AP and IP 3 /AM on follicular morphology, apoptosis, and ERS in D-gal-induced SWFs. ( A ) H&E staining on SWFs. Red arrow: GC layer. Scale bar: 50 μm. ( B ) TUNEL staining of SWFs. Apoptotic cells in green (TUNEL), nuclei in blue (DAPI). Scale bar: 50 μm. ( C ) Relative TUNEL index. ( D – H ) RT-qPCR detection of mRNA expression levels ( GRP78 , ATF4 , ATF6 , CHOP , and ITPR1 ). ( I – L ) Western blot detection and analysis of protein expression levels (IP 3 R, GRP78, and CHOP). Data are presented as mean ± SEM ( n ≥ 3). Protein and mRNA expression levels are normalized to the control group. Significant differences between groups are indicated by distinct lowercase letters ( p < 0.05).
Ip 3 R Agonist, supplied by Sirius Fine Chemicals, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/caged+ins+phosphate/pmc13024370-65-31-23?v=Sirius+Fine+Chemicals
Average 94 stars, based on 1 article reviews
ip 3 r agonist - by Bioz Stars, 2026-08
94/100 stars
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Effects of AP and IP 3 /AM on follicular morphology, apoptosis, and ERS in D-gal-induced SWFs. ( A ) H&E staining on SWFs. Red arrow: GC layer. Scale bar: 50 μm. ( B ) TUNEL staining of SWFs. Apoptotic cells in green (TUNEL), nuclei in blue (DAPI). Scale bar: 50 μm. ( C ) Relative TUNEL index. ( D – H ) RT-qPCR detection of mRNA expression levels ( GRP78 , ATF4 , ATF6 , CHOP , and ITPR1 ). ( I – L ) Western blot detection and analysis of protein expression levels (IP 3 R, GRP78, and CHOP). Data are presented as mean ± SEM ( n ≥ 3). Protein and mRNA expression levels are normalized to the control group. Significant differences between groups are indicated by distinct lowercase letters ( p < 0.05).

Journal: Antioxidants

Article Title: Apigenin Prevents Ovarian Aging by Regulating Ca 2+ -Mediated Endoplasmic Reticulum Stress in Laying Chickens

doi: 10.3390/antiox15030323

Figure Lengend Snippet: Effects of AP and IP 3 /AM on follicular morphology, apoptosis, and ERS in D-gal-induced SWFs. ( A ) H&E staining on SWFs. Red arrow: GC layer. Scale bar: 50 μm. ( B ) TUNEL staining of SWFs. Apoptotic cells in green (TUNEL), nuclei in blue (DAPI). Scale bar: 50 μm. ( C ) Relative TUNEL index. ( D – H ) RT-qPCR detection of mRNA expression levels ( GRP78 , ATF4 , ATF6 , CHOP , and ITPR1 ). ( I – L ) Western blot detection and analysis of protein expression levels (IP 3 R, GRP78, and CHOP). Data are presented as mean ± SEM ( n ≥ 3). Protein and mRNA expression levels are normalized to the control group. Significant differences between groups are indicated by distinct lowercase letters ( p < 0.05).

Article Snippet: SWFs were pretreated with a 10 μM concentration of AP for 24 h. A membrane-permeant myo-inositol-1,4,5-trisphosphate derivative (10 μM IP 3 /AM, CAT3-1-145, SiChem GmbH, Bremen, Germany) was employed as an IP 3 R agonist for the inositol 1,4,5-trisphosphate receptor (IP 3 R), a critical calcium release channel on the endoplasmic reticulum.

Techniques: Staining, TUNEL Assay, Quantitative RT-PCR, Expressing, Western Blot, Control

Effect of AP supplementation on the Ca 2+ channel and ERS in SWFs of D480 chickens. ( A – E ) RT-qPCR detection of mRNA expression levels ( CACNA1C , CACNA1D , ITPR1 , ATP2B1 , and CAMKII ). ( F – H ) Western blot detection and analysis of protein expression levels (IP 3 R, CACNA1C). ( I – L ) RT-qPCR detection of mRNA expression levels ( GRP78 , CHOP , ATF6 , and ATF4 ). ( M – O ) Western blot detection and analysis of protein expression levels (GRP78, CHOP). Data are presented as mean ± SEM ( n ≥ 3). Protein and mRNA expression levels are normalized to the control group. Significant differences between groups are indicated by distinct lowercase letters ( p < 0.05).

Journal: Antioxidants

Article Title: Apigenin Prevents Ovarian Aging by Regulating Ca 2+ -Mediated Endoplasmic Reticulum Stress in Laying Chickens

doi: 10.3390/antiox15030323

Figure Lengend Snippet: Effect of AP supplementation on the Ca 2+ channel and ERS in SWFs of D480 chickens. ( A – E ) RT-qPCR detection of mRNA expression levels ( CACNA1C , CACNA1D , ITPR1 , ATP2B1 , and CAMKII ). ( F – H ) Western blot detection and analysis of protein expression levels (IP 3 R, CACNA1C). ( I – L ) RT-qPCR detection of mRNA expression levels ( GRP78 , CHOP , ATF6 , and ATF4 ). ( M – O ) Western blot detection and analysis of protein expression levels (GRP78, CHOP). Data are presented as mean ± SEM ( n ≥ 3). Protein and mRNA expression levels are normalized to the control group. Significant differences between groups are indicated by distinct lowercase letters ( p < 0.05).

Article Snippet: SWFs were pretreated with a 10 μM concentration of AP for 24 h. A membrane-permeant myo-inositol-1,4,5-trisphosphate derivative (10 μM IP 3 /AM, CAT3-1-145, SiChem GmbH, Bremen, Germany) was employed as an IP 3 R agonist for the inositol 1,4,5-trisphosphate receptor (IP 3 R), a critical calcium release channel on the endoplasmic reticulum.

Techniques: Quantitative RT-PCR, Expressing, Western Blot, Control